Mulai dari | Rp. 8,877,702 |
Katalog | SLSRP3093-20UG |
Brand | Sigma Aldrich |
Kondisi | New |
Lampiran |
Katalog | SLSRP3093-20UG |
Ukuran | - |
Ketersedian | Hubungi Kami ![]() |
Harga | Rp. 8,877,702 |
IL-4 human
Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
Synonym: B cell stimulating factor (BSF-1), BCDF, BCGF
IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Recombinant human IL-4 is a 14.9 kDa globular protein containing 129 amino acid residues.
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a stabilizer (example 5% Trehalose) and store in working aliquots at -20°C to -80°C.
Lyophilized with no additives.
IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant human IL-4 is a 14.9 kDa globular protein containing 129 amino acid residues.
Related Categories | Cancer Research, Cell Biology, Cell Signaling and Neuroscience, Cytokines & Growth Factors,Cytokines and Growth Factors, More... |
recombinant | expressed in E. coli |
assay | ≥98% (HPLC) |
| ≥98% (SDS-PAGE) |
form | lyophilized |
mol wt | mol wt 14.9 kDa |
impurities | |
suitability | cell culture tested |
Swiss-Prot accession no. | P05112 |
shipped in | wet ice |
storage temp. | −20°C |
Gene Information | human ... IL4(3565) |
5 Stars | : 0 | 4 Stars | : 0 | 3 stars | : 0 |
2 Stars | : 0 | 1 Stars | : 0 |
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