The antibody labels keratinized and corneal epidermis, stratified squamous epithelia of internal organs, stratified epithelia, hyperproliferative keratinocytes, and simple epithelia. The antibody is useful for the identification of tumors as carcinoma or epithelial origin and for differential identification of undifferentiated carcinomas.

Merkel cell tumor. Some neoplastic cells show a focal and dot-like cytoplasmic staining reaction for cytokeratin.

Clinical application for IR053/IS053. For identification of tumors of epithelial origin such as squamous cell carcinoma, seminoma and Merkel cell tumor.

• Optimized staining performance of both high and low-expression structures
• Crisp and clear staining with no background
• Optimal laboratory efficiency with ready-to-use antibodies on Autostainer Link 48

The staining performance of all antibodies has been defined, tested and approved through collaboration with leading international pathologists. Check the Atlas of Stains - a guide to diagnostic accuracy.

Product	Size
	IR053 Clone AE1/AE3 Specification Sheet Safety Data Sheet: Non-hazard classification statement	60 tests, 12 mL  Product No. IR05361