Monoclonal Mouse Anti-Human

Epithelial Membrane Antigen (EMA)

Clone E29

Labels normal and neoplastic epithelium.

The antibody is very useful together with the monoclonal antibodies to leucocyte common antigen (Code M0701) and cytokeratin (Code M0821), which label cells of lymphoid and epithelial origin, respectively. In the classification of hematolymphoid neoplasms, the antibody labels Reed-Sternberg cells in nodular lymphocyte predominant Hodgkin's lymphoma and neoplastic cells in a subset of anaplastic large cell lymphomas.

Isotype IgG2a, kappa

• Frozen
• Formalin
• Enzyme/HIER

Breast ductal carcinoma (FFPE) stained with FLEX Anti-EMA, Code IR629/IS629.

Mesothelioma. The malignant mesothelioma cells show a strong staining reaction in membrane and cytoplasm.

Clinical application for IR629/IS629 For identification of tumors of epithelial origin in a wide variety of tissues.

Breast ductal carcinoma. The majority of the neoplastic cells show a moderate to strong membranous and cytoplasmic staining reaction.

Clinical application for IR629/IS629 For identification of tumors of epithelial origin in a wide variety of tissues.

Breast. Epithelial cells show a strong staining reaction on the apical part of the cell membrane and, occasionally, on the entire circumference of the cell membrane. A granular cytoplasmic staining reaction can also be observed.

Recommended control for IR629/IS629. Breast/Tonsil.

Tonsil. The squamous epithelial cells show a moderate to strong distinct cytoplasmic staining reaction, and the plasma cells show a weak to moderate predominantly membranous staining reaction.

Recommended control for IR629/IS629. Breast/Tonsil.

Colon adenocarcinoma stained with Anti-EMA.

Clinical application for IR629/IS629 For identification of tumors of epithelial origin in a wide variety of tissues.

 

	Product	Size
	M0613 Culture supernatant Specification Sheet Safety Data Sheet: Non-hazard classification statement	0.2 mL Product No. M061329
		1 mL Product No. M061301