| Rp. 2,362,819 |
Synonym: 1,1-Dimethylbiguanide hydrochloride, Metformin
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
Metformin is an antidiabetic agent that reduces blood glucose levels and improves insulin sensitivity. Its metabolic effects, including the inhibition of hepatic gluconeogenesis, are mediated at least in part by activation of the LKB1-AMPK (AMP-activated protein kinase) pathway. Activation of this pathway also appears to be involved in the antiproliferative and proapoptotic actions of metformin in cancer cell lines.
Certified Fluka® pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards
This product was designed, produced and verified for accuracy and stability in accordance with ISO/IEC 17025:2005 (AClass Cert AT-1467), ISO GUIDES 34:2009 (AClass Cert AR-1470).
FLUKA is a registered trademark of FLUKA GmbH
|Related Categories||Analytical Standards, Analytical/Chromatography,Chromatography, Pharmaceutical Secondary Standards, Pharmaceutical Standards More...|
|grade||certified reference material|
|pharmacopeia traceability||traceable to PhEur M0605000|
traceable to USP 1396309
|Precautionary statements||P305 + P351 + P338|
|Hazard Codes (Europe)||Xn|
|Risk Statements (Europe)||22-36/38|
|Safety Statements (Europe)||26-36|
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