Acclaim PolarAdvantage II Complementary selectivity and enhanced hydrolytic stability • Unique selectivity complementary to the C18 column • Novel polar-embedded column chemistry for hydrolytic stability • Compatible with 100% aqueous mobile phase • Low bleed for MS compatibility • Wide range of applications Acclaim PolarAdvantage II (PA2) columns feature a patented surface chemistry that incorporates an amide-embedded polar group and multi-point attachment between the ligands and the silica surface. This unique chemistry provides enhanced hydrolytic stability from pH 1.5-10 with 100% aqueous mobile phases and exhibits high reversed-phase capacity, with selectivity complementary to conventional C18 columns. The Acclaim PA2 column is specifically designed to withstand high pH conditions, making it a good choice for the separation of both basic and acidic analytes.