Acclaim Trinity P2 Mixed-mode column technology; hydrophilic interaction combining HILIC,anion exchange and cation exchange functionalities
• Ideal for separating pharmaceutical counterions, including monovalent and divalent cations or anions
• Selectivity complementary to the Trinity P1 column
• Low column bleed, compatible with CAD and MS
• Hydrolytically stable
• High efficiency
The Acclaim Trinity P2 is a unique, high-efficiency, silica-based column specifically designed for separation of pharmaceutical counterions, including monovalent and divalent cations or anions. This column is based on Nanopolymer Silica Hybrid (NSH) technology, which consists of high-purity porous spherical silica particles coated with charged nanopolymer particles. The inner-pore area of the silica bead is modified with a covalently bonded organic layer that provides cation-exchange retention, while the outer surface is modified with anion-exchange nano-polymer beads. Acclaim Trinity P2 column is aimed to complement Acclaim Trinity P1 to provide a total solution for pharmaceutical counter ion analysis by HPLC.